抄録
Superficial angiomyxoma is an unusual benign tumor that develops between the dermis and subcutaneous adipose tissue and originates from fibroblasts. We report a case of superficial angiomyxoma in the cheek region. The patient was a 44-year-old man who had noticed a cheek mass 4 years earlier but had not received treatment. The mass grew gradually, and the patient was thus referred to our hospital for surgical treatment. At the first visit, the patient's face appeared asymmetrical because of the nipple-shaped mass in the right cheek region. A biopsy did not provide an accurate pathological diagnosis. With a suspected diagnosis of benign buccal tumor, an operation was performed under general anesthesia. The excised specimen consisted of multiple globular clusters and had a smooth surface. Microscopic examination showed that the mucous component comprised spindle-shaped cells and fibrous tissue containing blood capillaries. Immunohistochemical analysis showed that the tumor cells were positive for CD34 and Factor XIIIa and negative for α-smooth muscle actin and S-100. The MIB-1 index was less than 1%. These results led to a final diagnosis of superficial angiomyxoma. The patient has not shown any sign of tumor recurrence to date (4 years after surgery).
