Follicular lymphoma is a type of non-Hodgkin's lymphoma and is classified as low-grade lymphoma owing to its slow progression. It rarely occurs in the sublingual gland, and only two cases have been reported to date: one case in Japan and the other case in the United States.
We report a case of follicular lymphoma arising in the sublingual gland. A 60-year-old woman presented to our department with a chief complaint of swelling of the left side of the mouth floor. Magnetic resonance imaging revealed a mass in the left sublingual gland. An incisional biopsy performed with the patient under local anesthesia led to a histopathological diagnosis of follicular lymphoma grade 2. Eight cycles of R-CHOP therapy were administered in our hospital's hematology department. The tumor underwent complete remission and disappeared after treatment. The patient is currently under observation in our department and the department of hematology in our hospital.
