非細菌性顎骨骨髄炎の診断と治療 −全身疾患との関連を含めて−

抄録

In this review, we describe the diagnosis and treatment of nonbacterial mandibular osteomyelitis, especially SAPHO syndrome which is associated with systemic disease, and diffuse sclerosing osteomyelitis(DSO) and chronic recurrent multifocal osteomyelitis(CRMO), which we are currently having difficulty in treating. Clinical images of CT, MRI and SPECT-CT are the mainstay of diagnosis in nonbacterial submandibular osteomyelitis, and the combination of systemic disease is a major clue. When a definitive diagnosis is obtained by biopsy, drug administration should be given priority and immediate invasive surgical treatment should be avoided.