抄録
After submandibular lymphadenectomy the opposite lymph node was transported to the vacant area as a free graft in the following experiments.
Experiment I: In C3H/He mouse a whole lymph node was transplanted. A lymph node of untreated mouse was used as control. At 1 week after transplantation the number of lymphocytes in the nodes was less than 0.1% of control. At 4 weeks it was increased to about 70% of control, and subpopulation was the same as the control. But mitogenic response to Con A, PHA, LPS was much lower. At 3 months the number was reduced again to about 12% of the control, and mitogenic response was not recovered. Finally most of the nodes degenerated.
Experiment II: In Vistar rat a lymph node was cut into two pieces and both were transplanted. A lymph node of untreated rat was used as the control. The transplanted lymph nodes were able to survive. At 1 week after transplantation the number of lymphocytes in the nodes was about 17% of control. The subpopulation was in disorder, and mitogenic response to Con A, PHA, LPS was much lower. After 4 weeks they tended to recover. At 3 months the lymphocyte number was increased to about 50% of the control. The subpopulation and the mitogenic response recovered the same as the contorol.
This study demonstrated that lymph nodes cut into two pieces can be transplanted as a free graft and lymphocytes circuration is restored.
