1989 年 35 巻 9 号 p. 2335-2342
Sixty-four-year-old male complained of the diffuse brown pigmentation of labial gingiva (3-3). The pathological diagnosis of biopsy specimen was melanosis.
A black tuberous solid mass was found in the same site 20 months later during the follow up period. As malignant melanoma was suspected, the extirpation (partial maxillectomy) of the tumor and postoperative adjuvant immunochemotherapy (DAV, OK-432) were done.
Six months later, metastasis was found in cervical lymph nodes. Radical neck dissection (RND) was performed and nodal involvements were pathologically recognized.
Two years after RND, he died of pneumonia. Neither primary recurrence nor distant metastasis were observed.