日本口腔外科学会雑誌
Online ISSN : 2186-1579
Print ISSN : 0021-5163
ISSN-L : 0021-5163
口腔粘膜メラニン色素沈着症より発生したと思われる悪性黒色腫の1例
野谷 健一山崎 裕水越 孝典戸塚 靖則福田 博進藤 正信安田 元昭飯塚 正雨宮 璋
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1989 年 35 巻 9 号 p. 2335-2342

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Sixty-four-year-old male complained of the diffuse brown pigmentation of labial gingiva (3-3). The pathological diagnosis of biopsy specimen was melanosis.
A black tuberous solid mass was found in the same site 20 months later during the follow up period. As malignant melanoma was suspected, the extirpation (partial maxillectomy) of the tumor and postoperative adjuvant immunochemotherapy (DAV, OK-432) were done.
Six months later, metastasis was found in cervical lymph nodes. Radical neck dissection (RND) was performed and nodal involvements were pathologically recognized.
Two years after RND, he died of pneumonia. Neither primary recurrence nor distant metastasis were observed.

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