PCNA score was measured in oral lesions including malignant tumors in a total of 108 cases, and the relationship of it to other cell proliferation markers, Ki-67, S phase fraction, AgNORs was also investigated. Average PCNA scores of 22.8% closely related to Ki-67 scores of 24.1% suggesting that PCNA positive cells represented not only S phase cells but also other cycling phases. The fact that PCNA scores was significantly different between malignant and nonmalignant lesions, suggested the difference in growth activity.
