A case of spindle cell lipoma of the tongue is presented. The patient, a 71-year-old man, had a painless swelling of the tongue. Physical examination revealed two discrete, tender masses in the left ridge of the tongue. These masses were removed surgically. Histopathologically, they consisted of small groups of mature lipocytes separated by spindle cells and of stroma to composed of bundles of collagen fibers and mucinous materials. The spindle cells had a single fusiform nucleus. The histopathological diagnosis was spindle cell lipoma. Spindle cell lipoma commonly arises in the posterior neck, upper back, and shoulders and is extremely rare in the oral cavity. Only nine cases have been reported in the literature.
