Metastatic tumors of the oral region are rare, comprising approximately 1 % of all malignant oral neoplasms. Their prognosis is generally poor. We report a case of metastatic renal cell carcinoma that initially presented as a tumor of the lower gingiva. The patient was a 68-year-old man who visited our department because of a swelling of the lower gingiva. Biopsy was performed, and gingival metastasis from renal cell carcinoma was strongly suspected on histopathological examination. Further examinations were performed. Renal cell carcinoma with metastases to the lung, cervical vertebrae, and ribs was diagnosed. Although the gingival metastatic tumor was relatively localized, marginal resection of the mandible was done under general anesthesia. The patient then underwent nephrectomy, radiotherapy, and interferon therapy at the department of urology. There has been no recurrence at the primary lesion or oral cavity, and the other metastatic lesions are well controlled.
