抄録
Clear cell carcinoma, not otherwise specified (NOS), is a rare malignant tumor of salivary gland origin that is composed of clear cells without features characteristic of other neoplasms. We report a case of clear cell carcinoma, NOS, in the retromolar region that arose from the minor salivary glands. The patient was a 45-year-old woman who had a painless swelling of the left molar region of the mandible. MR imaging revealed a mass inside the left mandibular ramus and showed bone resorption. Under a clinical diagnosis of a mandibular tumor, the mass was resected under general anesthesia. The solid and elastic hard tumor mass had a pale yellow cut surface. Histopathologically, the tumor consisted of clear cells containing diastase-digestive PAS-positive granules. The tumor cells were positive for cytokeratin and epithelial membrane antigen, but did not react with myoepithelial differentiation markers. In other abdominal organs, there was no abnormality on CT. On the basis of these features, the tumor was diagnosed as a clear cell carcinoma, NOS, originating from the minor salivary gland. Postoperative radiation therapy was performed for the primary focus with chemotherapy. At present, there has been no recurrence or metastasis of the tumor.
