抄録
Resembling lipstick,Lidocaine Stick (LS) is used for pinpoint anesthesia of the skin prior to invasive procedures in dermatology or plastic surgery treatments,and has been shown to produce a quick and sustained anesthetic effect.We designed a formula and preparation method for LS,and evaluated its anesthetic effect by conducting a prick test in volunteers and a clinical study in patients undergoing pimple excision.We were able to design a surfactant-containing oily formulation for LS and a preparation method for it.
The results of the prick test indicated that the anesthetic effect of a 60% LS was comparable to that of a commercially available tape preparation containing the same volume of lidocaine.In the clinical study on patients undergoing pimple excision,the 60% LS produced an anesthesia rate of 65.5%.Furthermore in a questionnaire survey,both volunteers and patients responded favorably with regard to the smoothness and ease of use of the 60% LS.
