病院薬学
Online ISSN : 2185-9477
Print ISSN : 0389-9098
ISSN-L : 0389-9098
血中ジゴキシン濃度中毒域の再検討
上野 和行宮井 一義
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ジャーナル フリー

1991 年 17 巻 1 号 p. 34-37

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Examination for digoxin toxicity was carried out on 46 Japanese inpatients with heart failure (age: 72.2±9.0) receiving routine oral maintenance digoxin therapy.Their serum digoxin concentrations were ranged 1.5-2.0ng/ml.It was found that 29 patients have evidence of digoxin toxicity.Age, body weight, serum digoxin concentration, and renal and hepatic function were not changed between toxic and non-toxic groups.Therefore, the data indicate that if serum digoxin concentration is above 1.5ng/ml, we must attend to the evidence of digoxin toxicity in Japanese.
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© 一般社団法人 日本医療薬学会
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