Changes of digital plethysmographic patterns following the administration of vitamin E, γ-oryzanol, sex hormone or tranquilizer for 2 to 4 months were investigated in 94 female cases of non-specific complaints ranging in age from 16 to 54. The results are summarized as follows : 1. In 29 cases whose complaints were induced by psychogenic caused, 16 cases (55.2%) of peripheral plateau wave, 5 cases (17.2%) of spastic wave, 3 cases (10.3%) of monophasic wave, 2 cases (6.9%) of bisferiens wave, 2 cases (6.9%) of dilatd wave and 1 case (3.4%) of anacrotic wave were observed before the therapy. In 65 cases whose complaints were induced by humoral imbalance due to the change of gonadial environment, 35 cases (53.8%) of peripheral plateau wave, 10 cases (15.4%) of bisferiens wave, 8 cases (12.3%) of spastic wave, 6 cases (9.2%) of dilated wave, 4 cases (6.2%) of monophasic wave and 2 cases (3.1%) of anacrotic wave were observed before the therapy.2. A normalization of digital plethysmographic patterns and a remarkable decrease of nonspecific complaints were not observed in almost all of the cases whose complaints were induced by psychogenic causes following the therapy. However, in cases whose complaints were induced by humoral imbalance, 18 cases of peripheral plateau wave, 4 cases of spastic wave, 4 cases of bisferiens wave, 4 cases of dilated wave and 1 case of anacrotic wave showed the normalization of digital plethysmographic patterns following the therapy. In addition, nonspecific complaints fairly disappeared concomitantly with an improvent of the digital plethysmographic patterns following the therapy in those cases.3. Clinical findings of 6 representative cases in which a close relationship between nonspecific complaints and digital plethysmographic patterns was shown in the course of the therapy are repreted.
