Muir-Torre症候群の脂腺癌に有棘細胞癌と基底細胞癌の合併を認めた１例

抄録

 Muir-Torre syndrome, a rare hereditary autosomal dominant cancer syndrome, is characterized by a predisposition to cancers of the colon and genitourinary tract, as well as skin lesions such as keratoacanthomas and sebaceous tumors. Herein, we report a case of an 87-year-old man with a history of colon cancer, who presented with an extraocular sebaceous carcinoma on the face in close proximity to his ear. We suspected Muir-Torre syndrome. We resected the tumor and histopathological examination of the resected specimen confirmed the presence of sebaceous carcinoma, squamous cell carcinoma, and basal cell carcinoma. We report a unique case of concomitant development of three types of malignant skin lesions at the same site. To our knowledge, this is the first report of this extremely rare condition.