2007 年 26 巻 1 号 p. 1-9
A large body of evidence suggests that oxygen free radicals may be important in either the primary or secondary pathophysiological mechanisms underlying stroke. The aim of this review is to provide an overview of the present clinical usefulness of biomarkers of oxidative injury in stroke patients. Measurement of biomarkers of oxidative injury for stroke should be used to provide biochemical evidence of antioxidant effectiveness. Exploration of the relationship between antioxidant profile and early outcome of stroke might provide new insights into the pathogenesis of stroke and open new therapeutic possibilities.