抄録
In 40 patients with malignant pleurisy associated with lung cancer, electrolytes, nitrogen compounds, lipid and enzymes in both pleural fluid and serum were measured to assess the permeability status of the pleural space in disease states.
The concentration ratios of pleural fluid to serum were nearly 1.0 in electrolytes, glucose, urea-N and ceratinine. However, the ratios of the concentration of total protein and immunoglobulins were less than 1.0 and inversely related to their molecular weight. It is suggested that the transfer of solutes into pleural space from vascular space was dependant on the size of the molecular weight.
The concentrations of amylase, bilirubin, carcinoembryonic antigen and lactic dehydrogenase were higher than the values estimated by their molecular weight. These elevations in pleural fluid are presumably attributed to hemolysis, associated inflamation and/or production by tumor cells in pleural fluid.
