抄録
Natural Killer (NK) activity was measured by 51Cr release assay in 33 patients with sarcoidosis and 54 healthy controls. The results were as follows:
1) In the control group, NK activity was independent of the donors' age. NK activity of the male in the control group was higher than that of the female, but statistically not significant.
2) NK activity in patients with sarcoidosis was significantly higher than in the control group, and was higher in the active stage than in the inactive stage.
3) NK activity increased in patients with bilateral hilar lymphadenopathy and/or pulmonary infiltration as compared to patients with no abnormal findings on chest roentgenography.
4) NK activity was suggested to be a useful index to evaluate the disease activity of sarcoidosis.
