The purpose of this study is to compare cytological findings of leiomyoma and leiomyosarcoma of the stomach. The two groups of 7 cases with leiomyoma and 4 cases with leiomyosarcoma were analysed Cytological materials were obtained by direct smear method from surgical specimen, and observed microscopically under 1000×magnification with Pap. staining.
1. leiomyoma cells: The means of the minor axis diameter of nuclei was found to be 4.6μ and narrowly distributed. Nuclei were cigar-shaped with rounded tips and contained normally stained granular chromocenters.
2. leiomyosarcoma cells: Nuclei of most cells were oval or rounded shaped and pleomorphic, containing deeply stained granular chromocenters and clumpy chromocenters.
The means of minor axis diameter was 7.5μ and showed a wide scattered distribution pattern.
It may be concluded that differential diagnosis by these cytological findings between leiomyoma and leiomyosarcoma could be made.