Cytologic findings of angiomyolipoma of the liver obtained by fine needle aspiration are described. The needle aspirates of the tumor revealed numerous fat cells, intermingled with endothelial cells and atypical cells which had eccentric round to oval nuclei with prominent nucleoli and slightly granular cytoplasm. Comparison with histology indicated that these atypical cells were of myoid type, and their cytoplasm stained positive for HMB 45. Thus, although angiomyolipoma of the liver is a rare tumor, it should be included in the differential diagnosis whenever we see tumors rich in fatty components as differentiation from malignant tumors is clinically important. In addition, immunocytochemistry with IIMB-45 is a valuable adjunct for correct diagnosis.
