Disturbance of visual function can result from causes such as cranial nerve disease, paranasal sinus disease, or malignant tumor. Accurate diagnosis and prompt treatment are important for disturbance of visual function, given the possibility of irreversible dysfunction. We report a case of malignant lymphoma of the paranasal sinus in which the initial symptoms and progress showed acute sinusitis-like symptoms. A 64-year-old man visited our hospital with a 3-day history of symptoms of right facial pain and swelling, fever, and diplopia. Blood examination showed findings of acute bacterial infection, and CT revealed right nasal and paranasal lesions. Endoscopic sinus surgery and transoral surgery were performed on the day of the first visit. Intraoperative findings included destruction of the infraorbital wall bone and exposure of the infraorbital nerve surrounded by tumor tissue. The pathological diagnosis was diffuse large B-cell lymphoma. Chemotherapy followed by surgical resection and anti-inflammatory treatment led to symptom improvement and remission. Medical staff should be aware that even acute inflammatory symptoms can be founded in other diseases such as malignant tumor.