抄録
It is anticipated that various problems of digestion and absorption occur after digestive surgery on neonates and infants, Among them, maldigestion and malabsorption of fats is most troublesome, but only a few reports provide concrete descriptions. In order to study digestion and absorption of fats, purified 131^I-triolein test was newly developed by us and performed in pediatric patients who underwent abdominal surgery. In this test, the "Digestion-Absorption Index" (triglyceride/non-esterified fatty acic of fecal fat) was calculated to differentiate fat maldigestion resulting from fat malabsorption. Exocrine function of the pancreas was also studied by pancreatic function diagnostant (PFD). Following results were obtained: 1) Difference in the digestibility and absorbability of fats occurred depending on the age of patients; in particular, the infants under the age of two months showed marked fat maldigestion and malabsorption. 2) In congenital biliary atresia (CBA) very severe fat maldigestion and malabsorption were seen, but the exocrine function of the pancreas was normal. 3) Infants with pancreatitis, either non-complicated or complicated, showed pancreatic exocrine disorder and fat maldigestion and malabsorption. 4) Among surgical patients with congenital intestinal atresia, all with a short small in-testine left behind, those without ileocecal valve showed marked fat maldigestion and malabs-orption, and a poor result of PFD test. 5) Among various cases of enterostomy, patients with ileostomy showed marked fat maldigestion and malabsorption, and a poor result of PFD test.
