Abstract
Clinical efficacy of Nolvasan surgical scrub (NSS) containing 2% chlorhexidine acetate in topical management of canine superficial pyoderma was evaluated. The study was designed as a randomized, double-blind, 10% ethyl lactate shampoo-controlled trial. Ten dogs with symmetric lesions of superficial pyoderma were allocated to either NSS or control product at different sites twice a week. These dogs were subjected by both owners and investigators, and skin lesions including pruritus, erythema, crusted papule, and scale were also scored in four grades. In both owners' and investigators' observation, NSS significantly improved skin lesions compared with the control (p<0.02). In score differences of each lesion, NSS significantly improved erythema (p<0.02) and crusted papule (p<0.05) compared to the control, but not pruritus and scale. No adverse reaction was observed in this study. Based on these results, it is indicated that NSS is an effective and safe topical therapy in dogs with superficial pyoderma.
