2011 Volume 17 Issue 2 Pages 85-88
A one-year-old, female toy poodle presented with a skin tear caused by a slicker brush. The skin was thin and movable, and the skin extension index was 21.2%. Histopathologic examination of the skin did not reveal any apparent morphological abnormalities. In electron microscope analysis, each collagen fascicle was wide spacing, and the fiber diameter was extremely heterogeneous. The findings were compatible with Ehlers-Danlos Syndrome. The dog also showed bilateral medial patellar luxations (GII), and dysplasia of the occipital bone and cervical vertebrae in X-ray. To the best of our knowledge, this is the first report of canine Ehlers-Danlos Syndrome with objective assessment of the skin and joints.