Comparison of Clinical Features between Latrogenic and Spontaneous Cushing's Syndrome in Dogs

Abstract

General and cutaneous signs of 40 dogs with Cushing's syndrome including 21 iatrogenic and 19 spontaneous cases were investigated. The most common findings were polyuria and polydipsia in 30 dogs (75.0%) consisted of 15 iatrogenic (71.4%) and 15 spontaneous (78.9%) cases, and alopecia in 25 dogs (62.5%) including 13 iatrogenic (61.9%) and 12 spontaneous (63.2%) cases. Prevalence rate of the other clinical features such as polyphagia, abdominal enlargement, panting, muscular atrophy, prominent vasculature, calcinosis cutis and thin skin were characteristically high in spontaneous Cushing's syndrome as compared to iatrogenic Cushing's syndrome.