Abstract
A 9-year-old spayed female Shetland sheep dog was presented because of chronic vaginitis and vulvar erosion with pruritis. Under the tentative diagnosis of infectious vaginitis, disinfection of the region and topical and general application of antibiotics were performed. The symptoms were alleviated to some degree without complete remission. The culture examination of vaginal secretion revealed several bacteria and Candida glabrata which was resistant to the antibiotics applied. Then, the antibiotics were switched to the eutherapeutic ones to the bacteria isolated, and oral administration of terbinafine hydrochloride and topical application of miconazole ointment were initiated. This resulted in remission of the symptoms with no further recurrence. Vulvo-vaginal infection of C. glabrata in this dog might be induced under the long-term chemotherapy for refrectory vulvo-vaginitis.