Serological Studies on the Pseudomonas aeruginosa Report II

抄録

Four mutants derived from a strain of Pseudomonas aeruginosa is studied on precipitation and complent fixation reactions with the following results:
1) Precipitin reaction with the isolated endotoxin reveals no common features between No.117 and No.134 strains. No.134 strain and No.145 strain are very similar, but No.58 strain shows a similarity only to No.134.
Homma's A and C strains are similar to No.134 strain, but bear no kinship to Homma's B and D strains.
2) The findings of complement fixation reaction reveals the endotoxig roft, N4a.117 is positive with No.134 (OH) and No.145 (OH) antisera and that No.117 endotoxin and that of No.58 strain show a similar response. The endotoxins of No.134, No.145, A, and -C strains show a similar reaction to one another. No.58 strain is analogous to B strain.
3) The specificity of O-antigen observed in agglutinin reaction (Report I) is also observed. in endotoxin. But this specificity is the most intensive in the precipitin reactin of endotoxin.
A similar specific reaction appears together with a comparatively wide ranged additional reaction. The range of this additional reaction generally corresponds to the result of precipitin and O-agglutinin reactions. But it is not always correspondent.
4) The results of agglutinin, precipitin, and complement, fixation reactions reveal that those which are positive in these reactions show high titers. Those which are positive in one or two of these reactions generally show low titers.