大脳辺縁系の光誘発電位に対する=干渉の特異性

抄録

Photic evoked potentials recorded in the visual cortex and lateral geniculate body to the conditioning electrical stimulation of the limbic system were investigated in 58 rabbits.
The conditioning electrical stimulation of the septum, hippocampus and latera l geniculate body with a train of high frequency (100Hz) inhibited cortical photic evoked potentials, whereas that with a train of low frequency (3-5Hz) facilitated them. Cortical photic evoked potentials following the conditioning electrical stimulation of the amygdala with a train of low frequency had tendency to be facilitated. However, the conditioning stimulation with a train of high frequency arbitrarily inhibited and/or facilitated cortical photic evoked potentials.
Relationships between the anatom ical designation of the septum and the interactions to the photic evoked potential were analyzed. The conditioning electrical stimulation of medial and lateral nuclei of the septum with a train of high and low frequencies produced attenuation and potentiation of cortical photic potentials respectively, whereas the conditioning stimulation of dorsal nucleus on the septum facilitated cortical evoked potentials irrespective to a train of high and low frequencies.
The photic evoked potentials in the la teral geniculate body following the conditioning electrical stimulation of the septum, amygdala and hippocampus had no tendency to be attenuated and/or facilitated irrespective to a train of high and low frequencies.
Lesions in the peni- and para-ventricular areas of the hypothalamu s, nucl, reuniens and mammillary body abolished these responses suggesting that these areas are the pathway mediating the projections of the rhinencephalon to the visual cortex via the mesencephalic reticular formation.