1956 年 8 巻 2 号 p. 111-123
On the third day after rabbits experimental hepatic disturbances following (1) the ligatur of common bile duct, (2) manipulating destruction of hepatic tissue, (3) oral adminisof CCl4, and (4) oral administration of chloroform, glucose is intravenously admininistered resulting in hyperglycemia simultaneously V. B2 complex consisting of 3 agents is administered, either three agents individually or in a whole mixture.
The results obtained are as follows.
(1) In the (1) group, hyperglycemia is clearly intensified following all administrations.
(2) In the (2) group, hyperglycemia is clearly diminished following all administrations.
(3) In the (3) group, hyperglycemia is markedly diminished in 90 minutes. following administration of VB2.
(4) In the (4) group, hyperglycemia is diminished following administration of VB2. (5)
It is assumed that the diminution is due to the inprovement of dysfunction of carbohydrate metabolism in the impaired hepatic tissues following administration of V. B2complex.