1956 年 8 巻 2 号 p. 161-173
Drug resistance or drug sensitivity was examined on Shigella bacteria picked from each colony grown on Endo-agar plates which had been inoculated from 15 dysenteric patients specimens collected in summer,1955. The drugs used in this experiment were Aureomycin, Chloramphenicol, Terramycin, Dihydrostreptomycin and Achromycin.
Although most Shigella strains isolated from non-treated patients possess a similar sensitivity to the antibiotics, those strains of the patients who had been previously administered with any antibiotic, or sulfonamide showed markedly varying sensitivity.
The resistance of Shigalla bacteria is irrespective of its type, group and severity of symptoms.
Most strains isolated from patients under treatment, especially those from patient of 3days treatment showed irregurality of sensitiveness, with a trend of increase in resistance.
The increase in the resistan ce was observed most markedly in those drugs which had been used for the present treatment.