Abstract
Anti-aging medicine, which is defined as life extension science by multidisciplinary scientific fields, is particularly important in aging societies such as Japan. The basic concept of anti-aging medicine includes prevention of aging in tissues/ organs, prevention of diseases and subsequent increase of quality of life. However, not only the prevention, but also the restoration of aged tissues/ organs should be important. Particularly for most of the aging population, the appearance related to aging of the face could be improved. Plastic surgery mainly offers the improvement of appearance by either surgical or non-surgical approaches, which specifically include blepharoplasty for blepharoptosis, rhytidectomy for aging face, intense pulse light, lasers, chemical peeling for pigmented lesions and facial fillers and botulinum toxin for wrinkles. Since all such procedures should be evidence-based, patients and physicians involved in this field should understand the mechanisms, indications and limitations of each treatment.