Abstract
While anti-aging medicine is the discipline aimed at achieving health and longevity, gynecological anti-aging is not limited to that. Menopausal disorders are mainly caused by the deficiency of estrogen. Estrogen deficiency produces various disorders including hot flash or sweating and increases the risk of hyperlipidemia, arteriosclerosis, and osteoporosis. To treat them, hormone replacement therapy is provided and its safety is being reaffirmed. In Japan, where there is a growing tendency for delayed marriage and childbirth, pre-pregnancy anti-aging is also important as a countermeasure to the falling birth rate. Ovarian anti-aging to prevent the decline in ovarian function requires a systemic and holistic approach. Anti-aging starting from the fetal period is based on the theory of DOHaD (developmental origin of health and disease). Since nutrition and environment during pregnancy are associated with lifelong disease at later stages, starting anti-aging during pregnancy is an efficient and effective approach to prevent adult diseases.