抄録
Objective: Electroconvulsive therapy (ECT) is a highly effective treatment for severe depression. However, one major complication of ECT is the potential for temporary cognitive impairment. The purpose of this retrospective study was to explore the relationship between postictal confusion (PIC) and interictal disorientation (IID) as well as to clarify whether PIC is related to the improvement in symptoms or not.
Materials: Patients with depression who were admitted to Juntendo University Hospital to receive ECT from April 2006 to January 2011 were recruited.
Methods: PIC and IID for each patient was observed. The Hamilton Rating Scale to assess depression (Ham-D) was employed in depressive patients. All assessments were performed prior to first ECT session and a week after the final ECT session.
Measurement and Results: Thirty-seven patients were registered, but eight patients were interrupted due to complications. PIC was associated with improvement of HamD (p=0.0459). IID prevalence was not significantly different between patients of PIC and non-PIC group.
Conclusions: PIC is associated with a greater improvement after ECT, and is not related to IID.
