2017 Volume 63 Issue 3 Pages 195-200
Nocturnal enuresis (NE) is common problem in children, and its prevalence rate is 20% among children aged 5 and, subsequently, 15% of children recover every year.
However, approximately 0.5% of adult populations remain unchanged.
The major pathogenic factors involved in NE are nocturnal polyuria, small bladder capacity and/or detrusor overactivity, and a high arousal threshold.
Desmopressin is the first-line medication for the patients with diuresis dependent nocturnal enuresis and its efficacy rates are nearly 70%. Enuresis alarm device is also commonly used especially for the patients with small bladder capacity and is effective for 65-70% of patients with NE.
For the patients who do not respond to desmopressin and enuresis alarm, anticholinergics or tricyclic antidepressants are used.
Japanese Society on Enuresis has recently revised the practical guideline for nocturnal enuresis in 2016.