REACTION OF S-ACYLTHIAMINE WITH THIOLS OR AMINES, TRANSACYLATION OF S-ACYLTHIAMINE

抄録

When O, S-diacylthiamine (II) was reacted with a compound having an active thiol group, the S-acyl group of (II) was easily transacylated to acylate the latter. From these results it may be assumed that, as a part of biochemical actions of thiamine, S-acetylcocarboxylase acetylates coenzyme A by transacetylation to form acetylcoenzyme A.