抄録
The S35 in various organs was determined after administration of TPD-S35 (inner), TPD-S35 (outer) and thiamine-S35 in the rats and the following results were obtained.
1. Distribution of the S35 of TPD-S35 (inner) and TPD-S35 (outer) differs according to the organ. The former is retained for a longer period of time in the liver and heart and the latter in the blood and intestinal tract.
2. It was found that the replacement ratio of S35 was higher in the heart and brain than in other organs, when TPD-S35 (inner) was given subcutaneously every day consecutively.
3. The accumulation of S35 in the organs was not increased when TPD-S35 (outer) was given subcutaneously every day consecutively, differing from that of TPD-S35 (inner) given in the same way.
