THE JOURNAL OF VITAMINOLOGY
Online ISSN : 2185-2553
Print ISSN : 0022-5398
EFFECT OF RIBOFLAVIN DEFICIENCY ON RAT ELECTRORETINOGRAM
小柳 達男曽根 清秀杉原 重孝田村 淳泰
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1966 年 12 巻 4 号 p. 281-285

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Weanling male rats were fed a 18% casein diet with and without riboflavin. After 6 weeks of feeding, electroretinogram in both riboflavin deficient and control rats were examined. The ratio of amplitude in b wave/a wave was found to decrease in deficient rats. After the rats in the deficient group were returned to a normal diet for 4 weeks, the ratio become comparable to that of control rats.
Microscopic examination revealed that succinic acid dehydrogenase activity which located densely in the border of outer plexiform and inner granular layers and also in the layer of rods and cones decreased remarkably in deficient rats.
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© THE VITAMIN SOCIETY OF JAPAN
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