抄録
Studies were performed to find out the vitamin B12 status in blood tissues of alloxan diabetic animals. It was found that diabetic animals maintaining higher levels of blood ketone bodies had an increased requirement of vitamin B12. The maximum requirement for the vitamin was found in diabetic animals getting a higher dose of acetoacetate. Hepatic constituents also changed adversely in order of level of ketone bodies in the diabetic animals. Some direct or indirect interrelationship between vitamin B12 with ketone bodies are suggested.