抄録
Test dose experiments were conducted on both undernourished and well-nourished boys. The mean thiamine or riboflavin excretion after the test dose was found significantly higher in undernourished boys than in the well-nourished. Administration of cocarboxylase or flavin-adenine dinucleotide, however, diminished the difference between both groups.
The authors ascribe the increased excretion of thiamine or riboflavin in undernourished boys after dosing to the decreased ability of phosphorylation in their bodies.