Journal of Nutritional Science and Vitaminology
Online ISSN : 1881-7742
Print ISSN : 0301-4800
ISSN-L : 0301-4800
EFFECT OF 8-AMINO-8-DEMETHYL-D-ARABOFLAVIN, 8-AMINO-8-DEMETHYL-D-RIBOFLAVIN AND 8-HYDROXY-8-DEMETHYL-D-RIBOFLAVIN ON MICE
松井 邦夫笠井 佐夫
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ジャーナル フリー

1974 年 20 巻 6 号 p. 411-420

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Diets containing AAF or ARF instead of RF were administered to RF-deficient mice and growth was followed, and after 9 days liver and kidneys were removed and weighed. No significant difference in growth was found between experimental and control (RF-deficient) groups. AAF significantly increased the weight percentage of liver to body weight, and the liver of some mice administered AAF or ARF had the appearance of fatty liver. In kidneys no difference in weight percentage and appearance was found between experimental and control group. The hair of mice administered ARF was nearly as clean as that of mice administered RF, although that of mice deficient in RF or ad-ministered AAF was dirty and had the appearance of being drenched. Mice administered HF per os or by subcutaneous injection were not distinguished from RF-deficient mice in growth, weight of liver and kidneys, and in appearance of hair.
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