抄録
The present study was conducted with growing rats to examine effects of addition of 0.3, 1.0, 2.5, and 500 L-cystine to 10 or 2500 casein diet on tissue ascorbic acid and on serum cholesterol, a-tocopherol, and ceruloplasmin activity. Addition of 0.3-1% cystine to 10% casein diet caused the maximum growth and addition of 5% cystine to 25% casein diet depressed the growth. Increases in liver levels of ascorbic acid and in serum levels of cholesterol and a-tocopherol were observed with addition of 5% cystine to 10 and 25% casein diets as compared to the diets without addition of cystine. Addition of 0.3-5% cystine to 10% casein diet and addition of 500 cystine to 25% casein diet caused a decreased activity of serum ceruloplasmin. The changes in liver ascorbic acid, serum cholesterol, and serum a-tocopherol and in ceruloplasmin activity by dietary cystine correlated with the changes in liver levels of non-protein sulfhydryl.
