Journal of Nutritional Science and Vitaminology
Online ISSN : 1881-7742
Print ISSN : 0301-4800
ISSN-L : 0301-4800
Biosynthesis of Pyridoxine: Origin of the Nitrogen Atom of Pyridoxine in Microorganisms
Keiko TANAKAKeiko TAZUYAKazuko YAMADAHiroshi KUMAOKA
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2000 年 46 巻 2 号 p. 55-57

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The amide nitrogen atom of glutamine was incorporated into pyridoxine in four eukaryotes, Emericella nidulans, Mucor racemosus, Neurospora crassa and Saccharomyces cerevisiae, and two prokaryotes, Staphylococcus aureus and Bacillus subtilis, but not in the fol-lowing prokaryotes, Pseudomonas putida, Enterobacter aerogenes and Escherichia coll. On the other hand, the nitrogen atom of glutamate was incorporated into pyridoxine in P. putida, E. aerogenes and E. coil, but not in S. aureus and B. subtilis. These results suggest that there are at least two different biosynthetic routes for pyridoxine and the difference does not depend on prokaryotes and eukaryotes.
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