抄録
A health examination was done on 17 workers engaged in painting with benzene mixtures. Items of the examination were counting of red and white blood cells, tests of protein, urobilinogen, and copropora phyrin in the urine, questioning to fellings of fatigue, headache, vertigo, general weakness, and intestinal disorders. Subjective symptoms were positive in many of them. In a few of them decreased blood cell counts and positive urobilinogen were found. Positive albuminuria and coproporphyrinuria were not found in any of them. On five subjects who had many subjective symptoms and showed decrease of blood cell counts, measurements were made as to relative number of constituent leucocytes, specific gravity and hemoglobin content of the blood, sugar and urobilinogen contents in the urine, just before, one week after, and at the end of the intravenous administration of thioctic acid of 25 milligrams a day for two weeks. During these two weeks marked increase of the red and white cell counts, specific gravity of the whole blood, and hemoglobin contents as well as marked decrease of urobilinogen out-put in the urine were noted. But, there was no improvement of the relative counts of the leucocytes.
