Abstract
Sorbitan laurate (SL) and co-polymer of alkyl-methacrylate and carboxybetaine-methacrylate (MBME) were added to ethanol solution of glyceryl pentadecanoate (PDG) to stabilize the supersaturation (or prevent precipitation) of PDG. From on ethanol solution of 0.079 mol/kg PDG, 0.057 mol/kg SL and 5.7 ×10-6mol/kg MBME, no precipitation of PDG occurred beyond 700 d.
The average diameter of particles composed of PDG, SL and MBME was determined as 27 nm in ethanol solution. The effects of combination of SL and MBME on the crystallization of PDG from ethanol were concluded due to the following ; Alkyl groups of SL and PDG are surrounded by sorbitan group of SL and glyceride group of PDG to form small aggregates of SL and PDG. These aggregates may have affinity forward ethanol. The hydrophobic group of MBME may combine with the aggregates of PDG and SL to, consequently disturbing their growth.
