抄録
92 cases of glomerulonephritis which were confirmed both by clinical course and by histological findings of renal tissues obtained by biopsy were studied. From histological findings, they were clas-sified as acute, elapsed acute, subacute, subchronic, chronic, chronic sclerosing and nephrotic glomerulo-nephritis. In acute glomerulonephritis, mild acute form, which had not almost been known, was observed and presence of subclinical form was proved. Acute inflammatory change was still observed in the glomeruli after 4-9 months following acute attack. The histolytic alterative lesion coexisting with exudative and proliferative change of glomerular capillaries indicated the chronic tendency of glomerulonephritis. In elapsed acute glomerulonephritis, subclinical form which mildly progressed from the onset was observed besides repairing stage of acute form, histological findings of kidney of the cases with clinical course of Volhard's "healing nephritis with a defect" were not so constant in focall lesion of glomeruli as he stated but rather showed diffuse slight lesion of them. The author found that subacute glomerulonephritis had to include severe type of subchronic glo-merulonephritis as well as traditional Lohlein's fulminant type, and that preceding to these stages there was a process called acute extramembranous glomerulonephritis.. From above results acute glomerulonephritis may be classified as benign and malignant by its clinical course and moreover classified to intramembranous and extramembranous type respectively. In subchronic glomerulonephritis the author described diffuse, axial and peripheral sclerosing types which developed on the process to the glomerular sclerosis. In the renal functions of chronic glomerulonephritis the differences between individuals were mar-kedly noticed. This fact can be explained from that the preservation of renal function for considerable period of time when glomerular change consists chiefly of axial sclerosis, and capillaries are kept dilated. 2 cases of secondary sclerosing glomerulonephritis without history of renal disease were thought to be essential malignant hypertension at first, but were diagnosed as secondary sclerosing glomerulonephritis by renal biopsy. In nephrotic glomerulonephritis the author showed that nephrotic syndrome could coexist with all types of glomerulonephritis except acute type, and concluded that nephrotic stage of glomerulonephritis was not proper concept. Among the cases which showed symptomes of lipid nephrosis clinically, 2 cases with subclinical and elapsed acute glomerulonephritis were diagnosed by renal biopsy. It is imagined that when these cases are exposed to nephrotic stimmulation, socalled lipid nephrosis and corresponding histologicall change may develop. From above mentioned various cases and types, the author studied the clinical developmental mode of human glomerulonephritis
