1988 Volume 79 Issue 6 Pages 1096-1102
The present study reports the results of treatment in 67 cases of renal cell carcinoma during the 10 years from 1977 to 1987. Overall 1, 3 and 5-year survival rates by Kaplan-Meier method were 79.8, 64.1 and 55.5 percents, respectively.
Several factors which might be related to prognosis were analysed. As a result, anemia, increased erythrocyte sedimentation rate, postive C-reactive protein, decreased serum albumin, elevated serum α1-globlin and mixed echo pattern were found to be poor prognostic factors. By pathological study, the stage and the histological grade of tumors were found to be significant prognostic factors, while the importance of cell type, structual pattern and microinfiltration as a prognostic factor was not clearly demonstrated.
The cases with renal cell carcinoma were treated with the combined adjuvant therapy of chemotherapy (FT 207, 5-FU or UFT) and nonspecific immunotherapy (OK-432: Picibanil) postoperatively. It appeared that the postoperative adjuvant therapy was useful for the improvement of prognosis.