The Journal of Protozoology Research
Online ISSN : 2434-7027
Print ISSN : 0917-4427
Monoclonal Antibodies Prepared against Theileria annulata-infected Bovine Cells Recognize an Infection-associated Antigen Expressed by the Infected Cells
W. DÖRFLINGERE. SCHEINJ. S. AHMED
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JOURNALS OPEN ACCESS

1992 Volume 2 Issue 1 Pages 25-33

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Abstract

A battery of monoclonal antibodies were produced in mice against Theileria annulata-infected cells. Two of these antibodies (IgM and IgG1) reacted specifically with the surface membrane of the infected cells but not with Con A-stimulated or unstimulated bovine peripheral blood lymphocytes (PBL). The antibodies could stain also clones which were derived from the cell lines tested in the present study. Similarly, they reacted with T. annulata-infected but not with uninfected sheep PBL. After removal of the parasites by treating the infected cells with the anti-theilerial drug buparvaquone, the antibodies were no more able to bind to the cells.

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© 1992 National Research Center for Protozoan Diseases, National University Corporation Obihiro University of Agriculture and Veterinary Medicine
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