The purpose of this paper is to introduce a new hemofilter developed in our laboratory.
The new hemofilter used as a hollow fiber type is made of polysulfon membrane with two layers, inside being a skin layer and outside a sponge layer.
This material was employed as hemofilter in an experiment using normal (n=12) and uremic (n=4) dogs.
The following property of this membrane was found, 1) UFR was 7-91/hr·m2 and UFRP was 20-25ml/hr·mmHg·m2 at TMP 350mmHg,
2)Low-molecular weight solutes such as urea and creatinine permeated freely through this membrane,
3)Albumin did not permeate,
4)This membrane was superior in thromboresistance to other membranes presently used.
In conclusion, a new membrane material was introduced as a hemofilter and the possibility of applying this membrane in clinical use is discussed.
