Dialysate flow rate has conventionally been determined at 500ml/min without any definite theoretical basis. In order to save consumption of dialysate, there is a reasonable need to develope a dialyser which achieve same performance with lower flow rate.
In present study, we developed a new type of dialyser which fits to this purpose. Actually, it is called lowflow dialyser able to achieve same efficiency with dialysate flow at 200ml/min.
In this design, the blood flows in parallel and dialysate in series through two bundles of hollow fiber.
Experiments were done in vitro and in vivo by uremic dog with successful results. Clinical test was also seccessful. The newly designed low flow dialyser is a mile stone for better artificial kidney.
