人工臓器
Online ISSN : 1883-6097
Print ISSN : 0300-0818
ISSN-L : 0300-0818
血漿分離器、血液濾過器の最適形状
松田 兼一竹沢 真吾酒井 清孝中西 光井上 政昭
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1981 年 10 巻 6 号 p. 924-927

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The purpose of this report is to propose the optimum shape of hemofilter and plasma separator in terms of mass transfer model.
The axial distribution of ultrafiltration rate (UFR) and sieving coefficient (SC) is theoretically derived by considering factors, which are the behavior of protein conc., blood flow rate, viscosity, diffusivity, membrane permeability, reflection coefficient and mass transfer coefficient. In order to examine this medel, Kiil Type module is designed to have 12 filtrate-sampling parts which are aligned axially. Cytochrome C solution is chosen to be filtered through cellulose acetate membrane in this module.
UFR decreases drastically after one-third from the inlet and SC maintains almost constant, which can be simulated successfully by the mass transfer model.
In the case of same membrane area, a module should be consequently divided into as many compartments as possible which have a wide and short membrane.

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