The purpose of this report is to propose the optimum shape of hemofilter and plasma separator in terms of mass transfer model.
The axial distribution of ultrafiltration rate (UFR) and sieving coefficient (SC) is theoretically derived by considering factors, which are the behavior of protein conc., blood flow rate, viscosity, diffusivity, membrane permeability, reflection coefficient and mass transfer coefficient. In order to examine this medel, Kiil Type module is designed to have 12 filtrate-sampling parts which are aligned axially. Cytochrome C solution is chosen to be filtered through cellulose acetate membrane in this module.
UFR decreases drastically after one-third from the inlet and SC maintains almost constant, which can be simulated successfully by the mass transfer model.
In the case of same membrane area, a module should be consequently divided into as many compartments as possible which have a wide and short membrane.