The technical consideration of cryofiltration

Abstract

In the cryofiltration the macromolecule filters having the pore size 0.2 need the cooling at 4°C. It is able to treat with cryofiltration using macromolecule filter at 15-25°C which have the pore size between 0.1 and 0.08. But the removal ratio has been influenced by the filtrate temperature. It is good for macromolecule filter having pore size 0.2 to treat with below 4°C in the two way method, also it is the best for macromolecule filter having 0.1-0.08 to treat with between 15-25°C in recirculation method.