Abstract
The mechanism of direct CO2 excretion using commercially available hemodialyzers was examined ex vivo. CO2 was excreted both in the form of CO2 and HCO-3. The excretion ratio of CO2 and HCO-3 was about 1:20 if a suitable dialyzer was selected. This result showed that acetate hemodialysis did not disturb blood pH because Henderson-Hasselbalch equilibrium was not changed by this methad. clinically this method was very effective to control post hypercapnic alkalosis state in the patients with chronic respiratory failure which is difficult to be controlled by conventional mechanical ventilation.
